• HOME PAGE
• ABOUT US
• OUR SERVICES
• PRINCIPLES OF THE TREATMENT
• CONTRACTS WITH EMPLOYERS
• OUR DOCTORS

• MOVIES
• HEALTH-PROMOTING CAMPAIGN
• RECOMMENDATIONS AND AWARDS
• HOW TO GET TO US

OZONE

Treatments with Heal Ozone give new opportunities in the liquidation of bacteria. In 40 seconds the progress of teeth caries is stopped and the cured surfaces undergo remineralisation. A process of biological self-healing is started.

The allotropic form of oxygen with a three-atom molecule. A light-blue gas of a very characteristic smell. Ozone is one of the most important gases present in the stratosphere surrounding our planet (at the height of 10-50 kilometres/6-30 miles). At the height of 20-30 km (12-18 miles) it has the largest concentration of one ozone molecule (O3) for 100,000 air particles (10 ppm - parts per million) and for this reason it is much better than on the Earth level, where it has the concentration of 0.03 - 0.04 ppm. In the higher layers of the atmosphere, some bonds in oxygen molecules can be broken after the energy of ultra-violet radiation is absorbed. As a result, free oxygen atoms are present, which react with oxygen molecules, which leads to the creation of ozone molecules. Ozone is a very effective filter against ultraviolet rays emitted by the Sun, which protects the surface of the Earth especially well from the access of high-energy UVB radiation. It is created from oxygen under the influence of atmospheric discharges (e.g. during storms) and under the influence of some chemical reactions (in coniferous forests when the turpentine is oxidised with the oxygen from the air). It is a very strong oxidiser. In the industry it is used for bleaching and disinfection (e.g. of drinking water), it can be also found as a result of the operation of xerographic printers and in solariums. Ozone was discovered in 1840 by a German chemist, Chrystian Friedrich Schönbein (1799-1868). It was obtained artificially for the first time by Werner von Siemens in Germany in 1857. The maximum allowable concentration of ozone is 200 µg/m3 or 0.1 ppm, and it cannot be exceeded for 8 hours a day and for 40 hours a week, as ozone can cause harm to the respiratory system and the mucous membranes of the organism. The allowable values may be different in different countries and they are not always obligatory.

OZONE IN GENERAL MEDICINE
In medicine it was used by C. Lendler in 1870 for the purification of blood - publications on this subject come from 1885 from dr. Charles J. Kenworth. The ozone used in medicine is always a mixture of pure ozone and pure oxygen. Ozone is never used directly in an inhaling form, as due to its extremely strong oxidising properties, it exerts toxic effect on body's cells in direct contact. According to scientific studies, it causes metabolism troubles and, in consequence, the death of lung epithelium cells. Depending on the selected way of application, ozone concentration can be between 1 and 100 µg/ml (0.05 - 5 % O3). Ozone used in medicine has strong bactericidal, fungicidal and virucidal properties. It is used for the disinfection of wounds of various kinds and in bacterial or viral diseases. In case of low concentrations, natural immunological skills of the organism are stimulated - ozone activates the immune system. Ozone is also a perfect stimulant of the circulation, and for this reason it is used in the treatment of circulation system diseases. Its influence is equally valuable in the animation and stimulation of organic functions. Responding to the activation of the organism caused by ozone, the immune system produces special protein substance, called cytokine, which has the function of a mediator regulating the size and type of immune response (as well as intermediate substances such as interferons and interleukins). These substances regulate inflammation states and the activity and maturation of immune system cells, commencing a massive process of positive changes in the immune system, which result in a counteraction and fighting of disease factors. This means that the application of ozone therapy is a wonderful method to activate the immune system in patients with lowered and/or no immunity. Thanks to the special properties of ozone, ozone therapy is used in three main areas of recommendation:

• treatment of circulation system conditions and in geriatrics,
• treatment of viral diseases such as hepatitis, cold sore and shingles,
• treatment of infected wounds which are difficult to heal, and of inflammations, such as:
  - open ulcerations of the legs (ulcus cruris),
  - intestinal inflammations: rectum inflammation (proctitis) and large intestine inflammation (colitis),
  - burns, infected wounds, fungal infections, and other.
• Ozone is used as an additional therapy, completing the treatment of various kinds of cancer. Ozone in small doses stimulates the immune system, in the so-called "basic self-chemotherapy" involving re-transfusion of ozoned blood into the patient's body, or "indirect self-chemotherapy" in the form of an injection into the inter-muscular system. To inform patients, specialists, therapists and all other interested persons about the latest achievements in the field of ozone therapy, an association called Medical Society for Ozone Application in Prevention and Therapy was set up, which associates members form all over Europe.

OZONE IN STOMATOLOGY

The oxidizing properties of ozone have also been found useful for stomatology. Scientific research proved, that ozone enters into reaction both with carious bacteria and their metabolites (oxidation of bi-molecules of the dental plaque by ozone given by the HealOzone device - M. Grootveld, E. Lynch, B. Mills, C. Smith, A. Baysan , C. J. Silwood; oxidation of the metabolites of carious bacteria by ozone given by the HealOzone device - C. Smith, E. Lynch, A. Baysan, C.J. Silwood, B. Mills, M. Grootveld, the antibacterial influence of ozone on micro-organisms of primary caries changes of the root In vitro A Baysan, RA Whiley, E Lynch).
Ozone causes oxidation of bacteria metabolites and makes them impossible to use by the developing bacterial flora. Thanks to its oxidising influence on some proteins, it causes the destruction of the cellular membrane of carious bacteria in the infected tooth or on the surface of mucous membrane. The ozone's influence on the surface of the primary carious change of the tooth root over 20 seconds reduces the bacterial flora by 99.9% (in vitro). The application of these possibilities of ozone therapy was impossible due to the toxic activity of ozone in the direct contact via the respiratory tract. It was only the development of the HealOzone device that made it possible to use ozone in stomatology. Baysan research showed, that the application of HealOzone makes any leakage of ozone to the oral cavity impossible (the safety of ozone therapy of root caries conducted with the application of HealOzone, E. Lynch, A. Baysan). What is more, over the recent years no side-effects of ozone therapy with the application of HealOzone have been noted in any of research centres and stomatology clinics.

THE HISTORY OF DEVELOPMENT

EDWARD J R LYNCH
Edward Lynch is a professor of the Maintenance Stomatology and Gerostomatology Department of Queens University Belfast and a Consultant of Maintenance Stomatology for Rogal Hospitals. He has gained his clinical experience over 22 years of work with patients. Professor Lynch educated also scores of young doctors over many years of academic work. Every year he is invited to give lectures during UK, European, Word Restorative Dentistry Meetings. He devoted his scientific career to the issues of maintenance stomatology and gerostomatology. As the subject of his doctorate he chose the issues of detection and treatment of root caries, and since then he has been the tutor of over 40 doctorates dedicated to this subject. In recognition of his work he obtained many awards and prizes. He is the editor-in-chief of the Gerodontology magazine, and he participates in editorial committees of several other science magazines. He has the function of the Secretary and Treasurer of GORG IADR and gives scientific lectures about the treatment of root caries for the University of Bristol. He is a member of many international organisations, such as International Society for Breath Odor Research and International Health Care Foundation, he also performs the function of a consultant for ADA. In the course of his career he has published over 400 papers in scientific magazines and books. He has specialisation in the following areas: Maintenance Stomatology, Endodonthics, Prosthodontia. However, what he enjoys most is scientific and clinical work in the group of wonderful doctors in Queens University in Belfast. One of his female candidates for doctor's degree was given there in 2002 the Basil Bibby Award of the IADR 2002 for her scientific paper on ozone therapy.

Achievements

2002 - Won first prize as a co-author and the leader of scientific work during International Association for Dental Research Meeting, Cariology Group in San Antonio (with Layla Na'Baba).
2003 - Won first prize as a co-author and the leader of scientific work during International Association for Dental Research Meeting, Geriatric Oral Research Group in Washington (with Aylin Baysan).
1999 - candidate for the award of UK Dentist of the Year, Probe Awards.
1998 - Won first prize as a co-author of a scientific work during Annual Research Meeting of the Teachers of Conservative Dentistry ( with Shaz Yeganeth).
1994 - PhD - University of London.
1992 - Honorary title of MA - Trinity College Dublin.
1992 - Won the Association for Dental Research Division Post-Doctoral Hatton Travel Award.
1983 - Won the Greer Walker Prize during British Postgraduate Medical Federation Meeting.
1983 - FDSRCS Edinburgh
1983 - Completed Vocational Training for General Dental Practic

Correspondence address: Division of Restorative Dentistry,
Dental School
Royal Victoria hospital
Belfast
Northern Ireland

THE DESCRIPTION OF THE DEVICE
The HealOzone system consists of:
- a console,
- a foot switch,
- a contra-angle handpiece attached by means of a sleeve,
- disposable silicone caps.

The console contains an electronic display and regulator allowing to specify and control the time of administering ozone in the following periods: 10 s, 20 s, 30 s, 40 seconds.

The foot switch enables ergonomic and hygienic work with the device.

The contra-angle handpiece resembles a standard stomatological contra-angle handpiece KaVo and is similarly ergonomic and easy to use.

The silicone caps are of single-use (are not sterilised in the autoclave).
They are produced in five sizes, what makes it possible to adjust them
to the surface of any tooth.

The whole system includes fluid initialising the remineralisation of the tooth as well as n oral cavity hygiene kit for the patient, including toothpaste, irrigating fluid and a spray accelerating remineralisation.

OZONING
OZONING 1. Regulate of ozoning time on the display



HealOzone:
10 sec., 20 sec., 30 sec., 40 sec.

2. Select of a silicone cap of the right size, so that it were possible to seal it around the ozoned surfaces.

3. Place the cap on the ending

4. Put the cap tightly around the ozoned surfaces of the tooth.

5. Start the device by means of the foot pedal.
6. Apply the fluid initialising remineralisation on the ozoned tooth surfaces.

Ozone therapy - maintenance stomatology

Ozone therapy is mainly used in maintenance stomatology, to cure the caries changes in teeth. The influence of ozone is very effective in many clinical cases, and it includes: treatment of primary caries changes in even and biting surfaces of the teeth, treatment of primary root caries (instead of the traditional method of mechanical development and filling the defects), treatment of medium and deep caries (as a completion of mechanical development of defects). Treatment of primary carious changes. Professor Lynch and Dr. Holmes developed a detailed procedure to be applied in case of ozone therapy of primary caries. It includes the performance of the following sequence of clinical procedures:

1. Thorough cleaning of the examined tooth surfaces, in case of furrows on the biting surface it is recommended to use preventive sand machine (KaVo PROPHYflex 3).
2. Detailed examination of the surfaces of the teeth suffering from caries. The most effective way of diagnosis is, in this case, diagnostic laser (KaVo Diagnodent), which measures the degree and depth of demineralisation of teeth enamel, which allows to specify the progress of caries also in case of furrows in molar teeth.
3. The evaluation of clinical advancement of the carious change and planning ozone therapy. In order to perform ozone therapy in the proper way, it is best to use the CSI index developed by professor Lynch (Clinical Severity Index)

Evaluated carious changes and their treatment with traditional methods. Recommended time of ozoning the change.

1. Carious changes requiring the mechanical completion of the defect and filling (the presence of demineralised and infected carious dentine can be noted) 40 s.
2. Carious changes which may require completion of tooth tissues (the carious process reached the border of enamel and dentine, also demineralisation of the dentine under the enamel layer can be expected) 30s.
3. Changes requiring treatment by providing fluorine (the carious process is developing in the enamel, but it did not cross the enamel/dentine border, or there is a carious process in the stage of primary demineralisation) 20 s.
4. Carious changes stopped (the carious process was stopped in the enamel or on the enamel/dentine border, and changes in teeth tissues undergo remineralisation, no infected dentine is found under the enamel) 10s.
5. Treatment of changes by means of ozone therapy (general rules of ozone therapy), time of ozoning as prescribed.
6. Covering the ozoned tooth surfaces with the fluid initialising remineralisation (general rules of ozone therapy).
7. Conduct a hygienic instruction with the patient and, possibly, provide him/her with an oral cavity hygiene kit, accelerating remineralisation.
8. Patient's check-up after 4-6 weeks allowing to note the progress of remineralisation of tooth tissues or, possibly, to make a filling due to aesthetic reasons.

Scientific studies:
Application of ozone for the treatment of primary carious changes in teeth furrows (PCCTF) - clinical results.
Clinical results of the treatment of root caries by means of ozone therapy after 18 months.

HealOzone device gives ozone to the ending thanks to created negative pressure, due to which there is no risk of pushing the gas beyond the root top. Ozone should act as an extremely effective agent, disinfecting the tooth canal. Unfortunately, at present there is no scientific research describing clinical effects of ozone therapy conducted this way.

Prosthodontia

In prosthodontia ozone is widely used at the making of permanent prosthetic fillings such as crowns or bridgeworks. It is possible to ozone the prosthetic pillar before the filling is placed on it, in order to disinfect it thoroughly. In this way the risk of secondary caries under the prosthetic filling can be minimised.

Periodontology

Ozone is a strong bactericide, it also has fungicidal and virucidal properties. In the future it will be certainly possible to use ozone therapy in the treatment of viral changes (such as cold sore) on the mucous membrane.
Ozone is a strong bactericide, it also has fungicidal and virucidal properties. The potential influence of ozone on a wound created after surgical interventions should prevent the presence of complications connected with infections of the wound and accelerate its healing. Unfortunately, at present there is no scientific research describing clinical effects of ozone therapy conducted this way.

Implantology

Ozone is a strong bactericide, it also has fungicidal and virucidal properties. The potential influence of ozone on a wound created after surgical interventions should prevent the presence of complications connected with infections of the wound and accelerate its healing.

All scientific research are available in full at www.the-o-zone.com